Some songbirds, squirrels, and small mammals feed on White Pine seeds. Bark and foliage are consumed by beaver, snowshoe hares, rabbits, porcupines, red and gray squirrels, mice, and white-tailed deer. Bears use large White Pines as escape cover for their cubs and they use young dense stands for shelter during inclement weather. They provide habitat, particularly for eagles and osprey who use them for nesting and also as perches to scan for prey, since they tend to tower above other surrounding trees. Also used by pileated woodpeckers, lynx, a myriad of insects and fungi.
Of the pines, Eastern white is the softest and lightest, with white sapwood and straw brown to light red brown heartwood that weathers to light gray. Straight grained, uniform textured and homogeneous, it works easily with hand and machine tools and accepts fasteners, glue, and paint well. It is used extensively for windows, sashes, frames, doors, cabinetry, interior trims of boats, caskets, toys, carvings, and other woodenware.